In order to install MS AJAX you neet to log into your server (COMPLETELY SEPARATE FROM DNP)
You can either RDP (Remote Desktop) OR walk up to it, and log in.
Then you run the FREE Installer and voila MS AJAX is active across your ENTIRE server.
You can now develop rich AJAX enabled websites using the ME AJAX extensions (note that you also need to install AJAX on your development machine). There is NOTHING you need to do with DotNetPanel EVER.
Chase

DotNetPanel 2.8.5
Server 2008 Std
SQL Server Express
MailEnable Enterprise 3.14