Hi guys,
From 2.8.10 version DNP application pool cannot run x32 bit mode if you plan to manage web sites and use IIS remote management feature.
On the other hand if you use MailEnable, Merak, MDaemon or hMail, you should run your application pool in x32 bit mode.
We suggest workaround here to run 2 instances of DNP Server on different ports (no extra license needed). You just manually create new web site in IIS.
Let's name it "DNP Server (x32)", point it to the same code base as installed DNP Server. Create application pool for it and switch it to x32 mode.
Add it in DNP and then make a virtual server with combination of IIS service from server running x64 mode and mail server from server running x32 mode.
Other thing that you should update existent services in database that used old mail service. It is easy to do in table [dbo].[ServiceItems] changing
ServiceID.
This is all we can suggest here because it is platform design when we cannot use x64 mode with several mail providers and cannot use x32 mode with IIS.
If you have any questions, post them here, please.